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Machine Learning Engineer

Company: Terray Therapeutics
Location: San Gabriel
Posted on: January 12, 2021

Job Description:

Company Overview: Terray Therapeutics is a venture backed biotechnology company utilizing a novel spatially encoded screening and optimization platform to develop treatments for historically intractable causes of human disease. The Company's platform technology provides comprehensive, quantitative affinity binding data at a completely unprecedented scale. Our internal development programs are focused on oncology and immunology. In addition to these programs we also work with leading pharmaceutical companies. Our platform is based on fluorescent imaging of ultra-dense microarrays such that, via thousands to millions of images, we can measure billions of target/molecule interactions in a day, generating hundreds of millions of dose-response binding curves. Position Summary: Terray Therapeutics is seeking a motivated, creative, and experienced Machine Learning Engineer. As an integral member of our data team, the candidate will be responsible for developing and deploying state-of-the-art machine learning models trained on up to billions of small molecule affinity/activity data points in order to accelerate internal drug discovery efforts. The position will report to the Head of Computational and Data Sciences. The core responsibilities of this job will be: Develop multi-task machine learning models for predicting target affinity from molecular structure Work with computational chemists to develop novel molecular representations/features Develop deep learning anomaly detection methods to flag outliers in our image processing pipeline Develop a cloud-based training/inference platform for deploying large-scale production models Develop an active learning library design framework for integration of predictive models into an iterative hit discovery cycle Experience and Qualifications: Given the company's size, anticipated growth and fast-paced environment, the organization requires a machine learning engineer who is thoughtful, high energy and can partner with the broader organization to further enhance our next generation drug discovery capabilities. Part of Terray Therapeutics' success is nurtured by a hands-on work environment where everyone is accountable, everyone is vested in a vision of excellence, and everyone actively takes part in the success of the business. Terray Therapeutics supports a positive work environment comprised of engaged employees who feel appreciated, recognized and free to be creative. Qualifications include: PhD in Computer Science, Applied Math, Computational Chemistry, or related quantitative field Experience with traditional machine learning methods (e.g., SVM), ensemble methods (e.g., random forest, gradient boosting), as well as deep learning methods (e.g., GNNs) Experience with scalable machine learning on GPUs, including applications to large datasets Highly proficient in Python and the PyData stack (numpy, pandas, scipy, dask, etc.) Highly proficient in scikit-learn, XGBoost, and either PyTorch or TensorFlow Familiar with AWS cloud resources (S3, EC2, Batch, SageMaker) She/he will exhibit the ability to work well under pressure to provide results in a short timeframe. The company is looking for a highly responsive, goal-oriented individual who will bring significant energy and drive to solve complex technical problems and help us achieve our mission to advance human health.

Keywords: Terray Therapeutics, San Gabriel , Machine Learning Engineer, Engineering , San Gabriel, California

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